LDDist : a Perl module for calculating LogDet pair-wise distances for protein and nucleotide sequences

• Summary: LDDist is a Perl module implemented in C++ that allows the user to calculate LogDet pair-wise genetic distances for amino acid as well as nucleotide sequence data. It can handle site-to-site rate variation by treating a proportion of the sites as invariant and/or by assigning sites to different, presumably homogenous, rate categories. The rate-class assignments and invariant proportion can be set explicitly, or estimated by the program; the latter using either of two different capture–recapture methods. The assignment to rate categories in lieu of a phylogeny can be done using Shannon–Wiener index as a crude token for relative rate.

Ämnesord

NATURVETENSKAP  -- Biologi -- Bioinformatik och systembiologi (hsv//swe)

NATURAL SCIENCES  -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)

Nyckelord

Bioinformatics

Bioinformatik

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