Pyrazole-inducible proteins in DBA/2 mouse liver bind with high affinity to the 3'-untranslated regions of the mRNAs of coumarin hydroxylase (CYP2A5) and c-jun

• An important mechanism in the up-regulation of cytochrome P-450 2A5 (CYP2A5, coumarin hydroxylase, Coh) is the stabilization of the corresponding mRNA; some evidence suggests that proteins binding to CYP2A5 mRNA may be involved in this stabilization. Her

Nyckelord

MESSENGER-RNA STABILIZATION; AFLATOXIN B-1; METABOLIC-ACTIVATION; HAMSTER LIVER; RICH RNA; EXPRESSION; 7-HYDROXYLASE; 2A6; INDUCTION; GENE

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