The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: Function and regulation

• A large body of evidence has been accumulated that demonstrates dominant effects of Myc proto-oncoproteins on different aspects of cellular growth, Myc is one of the few proteins that is sufficient to drive resting cells into the cell cycle and promote DN

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Myc; DNA binding; E box; transcription; genes; CASEIN KINASE-II; TRANSCRIPTION FACTOR AP-2; C-MYC/MAX HETERODIMERS; BOX-BINDING PROTEINS; DNA-BINDING; IN-VIVO; N-MYC; RAS COTRANSFORMATION; HELIX PROTEIN; EPIDERMAL DIFFERENTIATION

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