Common and dysplastic naevi as risk factors for cutaneous malignant melanoma in a Swedish population.

• Common naevi, dysplastic naevi (DN) and other phenotypic features were evaluated as melanoma risk factors in a Swedish case-control study. One-hundred and twenty-one prevalent melanoma cases and 378 randomly selected controls participated. The mean total body naevus count was 115 in the cases and 67 in the controls. Fifty-six per cent of the cases and 18% of the controls had clinical DN. The corresponding figures for histologically diagnosed DN were 40% and 8% respectively. Clinical DN was as good as histologically diagnosed DN in identifying individuals at risk for melanoma. Subjects with sun-sensitive skin, greater than or equal to 150 naevi and presence of DN have 50 times higher melanoma risk than those without these characteristics.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Adult

Case-Control Studies

Dysplastic Nevus Syndrome

complications

epidemiology

Female

Humans

Male

Melanoma

epidemiology

etiology

Middle Aged

Nevus

complications

epidemiology

Risk Factors

Skin Neoplasms

epidemiology

etiology

Sunlight

adverse effects

Sweden

epidemiology

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)