A controlled study of tryptophan and cortisol in violent offenders.

• Changes in the metabolism of tryptophan, other amino acids, and steroid hormones have been implicated in aggression. We compared tryptophan, competing long amino acids (CAAs), and cortisol in serum (S) and CSF in 22 violent offenders and 15 healthy controls. Offenders had significantly increased S-L-tryptophan, S-free tryptophan, S-CAAs, S-cortisol and CSF-cortisol, indicating abnormal neurophysiological processes. Larger studies on the interplay between violence, serotonin precursors, and stress hormones need to integrate personality traits, life situations, and physiological adaptation.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)

Nyckelord

Adolescent

Adult

Aged

Aggression

physiology

Amino Acids

analysis

Antidepressive Agents

Second-Generation

analysis

Humans

Hydrocortisone

analysis

Male

Middle Aged

Tryptophan

analysis

Violence

performance liquid-chromatography

neutral amino-acids

habitually violent

plasma

availability

personality

alcoholism

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)