Pneumoproteins and inflammatory biomarkers in asphalt pavers.

• Pneumoproteins, biomarkers of systemic inflammation and endothelial activation were studied across a season in 72 asphalt pavers, 32 asphalt plant operators and 19 asphalt engineers. Smokers had lower concentrations of Clara cell protein (CC-16) and surfactant protein A, but higher concentrations of surfactant protein D, interleukin 6, C-reactive protein, fibrinogen and intercellular adhesion molecule (ICAM)-1 than non-smokers. Smokers reporting wheezing had lower mean CC-16 concentration than smokers not reporting wheezing (5.7 vs 8.6 microg l(-1); p = 0.05). Cholesterol, P-selectin and ICAM-1 were lower in pavers and operators at the end compared with the start of the season. This may be related to increased physical activity during the season.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)

Nyckelord

Adult

Biological Markers

analysis

Cell Adhesion Molecules

analysis

Construction Materials

Cytokines

blood

Endothelium

Vascular

physiology

Enzyme-Linked Immunosorbent Assay

Female

Fibrinogen

Humans

Hydrocarbons

Inflammation

metabolism

Interleukin-6

Linear Models

Lung

chemistry

Male

Middle Aged

Norway

epidemiology

Obesity

complications

epidemiology

Occupational Exposure

analysis

P-Selectin

Proteins

chemistry

Questionnaires

Respiratory Function Tests

Respiratory Tract Diseases

epidemiology

Seasons

Smoking

epidemiology

Spirometry

Young Adult

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)