Long-term outcome of microscopic esophagitis in chronic GERD patients treated with esomeprazole or laparoscopic antireflux surgery in the LOTUS trial.

• Gastroesophageal reflux disease (GERD)-associated changes in esophageal histology have been reported mainly after short-term medical antireflux therapy, and few individual lesions have been examined. We report detailed histological findings from the LOTUS study, at baseline and at 1 and 3 years after laparoscopic antireflux surgery (LARS) or esomeprazole treatment in patients with chronic GERD.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

Adult

Age Distribution

Biopsy

Needle

Chronic Disease

Esophageal pH Monitoring

Esophagitis

Peptic

epidemiology

etiology

pathology

Esophagoscopy

methods

Female

Follow-Up Studies

Fundoplication

adverse effects

methods

Gastroesophageal Reflux

diagnosis

drug therapy

surgery

Humans

Immunohistochemistry

Incidence

Kaplan-Meier Estimate

Male

Middle Aged

Omeprazole

administration & dosage

adverse effects

Probability

Risk Assessment

Severity of Illness Index

Sex Distribution

Statistics

Nonparametric

Time Factors

Treatment Outcome

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)