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Comparing patients ...
Comparing patients with Apert and Crouzon syndromes--clinical features and cranio-maxillofacial surgical reconstruction.
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- Stavropoulos, Dimitrios (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Tarnow, Peter, 1963 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery
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- Mohlin, Bengt, 1944 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Kahnberg, Karl-Erik, 1941 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Hagberg, Catharina, 1949 (författare)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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(creator_code:org_t)
- 2012
- 2012
- Engelska.
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Ingår i: Swedish dental journal. - 0347-9994. ; 36:1, s. 25-34
- Relaterad länk:
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Abstract
Ämnesord
Stäng
- Cranio-maxillofacial malformations, as seen in Crouzon and Apert syndromes, may impose an immense distress on both function and aesthetics of the person affected. The aims of this study were to describe and compare the main facial and intraoral features of patients with Apert and Crouzon syndromes, the clinical manifestations that may be present, additionally to the main syndromic traits, as well as the cranio-maxillofacial surgical treatment protocols followed.Twenty-three patients with Apert syndrome (6 males, 17 females), and 28 patients with Crouzon syndrome (20 males, 8 females) were evaluated for general medical aspects, craniofacial characteristics, dentoalveolar traits before and after the final orthognathic surgery, and types and timing of cranio-maxillofacial operations. Mental retardation, associated additional malformations, cleft palate, and extensive lateral palatal soft tissue swellings were more common in children with Apert syndrome. In both syndromes, clinical findings included concave profile, negative overjet, posterior crossbites, anterior openbite, and dental midline deviation, which were corrected in almost all cases with the final orthognathic surgery, with the exception of the lateral crossbites, including more than one tooth pair, which were persisting in about half of the cases. Cranial vault decompression and/or reshaping, midfacial and orbital advancement procedures, often in conjunction with a mandibular setback, were the most frequent cranio-maxillofacial operations performed. In conclusion, Apert syndrome is more asymmetric in nature and a more severe clinical entity than Crouzon syndrome. The syndromic dentofacial features of both conditions could be significantly improved after a series of surgical procedures in almost all cases with the exception of the posterior crossbites, with haIf of them persisting post-surgically.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Acrocephalosyndactylia
- pathology
- surgery
- Adolescent
- Child
- Child
- Preschool
- Confidence Intervals
- Craniofacial Dysostosis
- pathology
- surgery
- Facial Bones
- abnormalities
- surgery
- Facies
- Female
- Hearing Loss
- Humans
- Infant
- Intellectual Disability
- Lip
- abnormalities
- Male
- Malocclusion
- surgery
- Orthognathic Surgical Procedures
- Palate
- Hard
- abnormalities
- Sex Ratio
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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