An in vitro and in vivo Comparison of the Effect of Stevia rebaudiana Extracts on Different Caries-Related Variables: A Randomized Controlled Trial Pilot Study

• The effect of Stevia extracts on in vitro Streptococcus mutans biofilm formation and in vivo plaque pH was evaluated in this paper. Three 10% solutions containing stevioside, rebaudioside A or sucrose were prepared. MIT assay was used to evaluate microbiological counts in vitro. Twenty volunteers rinsed for 1 min with each solutions, and plaque pH was measured at 7 time points after each rinse. Higher in vitro S. mutans biofilm formation was observed in sucrose solution (p < 0.01). After 5, 10, 15 and 30 min, the sucrose in vivo rinse produced a statistically significantly lower pH value compared to the Stevia extracts (F = 99.45, p < 0.01). Stevia extracts can be considered nonacidogenic. (C) 20135. Karger AG, Basel

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Nyckelord

Caries

Plaque pH

Rebaudioside A

Stevioside

INTENSE NATURAL SWEETENERS

DENTAL-CARIES

PLAQUE-PH

STEVIOSIDE

SWEETNESS

SUCROSE

2-YEAR

RISK

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)