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In vitro platelet f...
In vitro platelet function in infantile autism.
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Safai-Kutti, Soodabeh (författare)
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Denfors, I (författare)
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- Kutti, Jack (författare)
- Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine
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visa fler...
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- Wadenvik, Hans, 1955 (författare)
- Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine
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visa färre...
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(creator_code:org_t)
- 1988
- 1988
- Engelska.
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Ingår i: Folia haematologica (Leipzig, Germany : 1928). - 0323-4347. ; 115:6, s. 897-901
- Relaterad länk:
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https://gup.ub.gu.se...
Abstract
Ämnesord
Stäng
- It has previously been demonstrated that patients with infantile autism demonstrate impaired in vivo platelet behaviour. Therefore, in 14 children (13 boys and 1 girl) with infantile autism (aged 2-14, mean 6 years) and 12 healthy control boys (aged 6-15, mean 11 years) we studied in vitro platelet reactivity using ADP- and collagen-induced platelet aggregation. In each child a total of 7 different final concentrations of ADP and 4 different concentrations of collagen were employed. At all concentrations of ADP and collagen used the autistic children consistently exhibited diminished platelet aggregability; the differences, however, did not reach statistical significance. Therefore a wider panel of in vitro tests is apparently required and a larger group of patients be studied to help elucidate the functional/metabolic platelet defect met in infantile autism.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Adolescent
- Autistic Disorder
- blood
- Child
- Child
- Preschool
- Female
- Humans
- Male
- Platelet Aggregation
- Platelet Count
- Platelet Function Tests
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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