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The emerging role o...
The emerging role of extracellular vesicles as biomarkers for urogenital cancers.
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Nawaz, Muhammad (author)
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Camussi, Giovanni (author)
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- Valadi, Hadi, 1963 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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Nazarenko, Irina (author)
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- Ekström, Karin, 1978 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Wang, Xiaoqin (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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Principe, Simona (author)
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Shah, Neelam (author)
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Ashraf, Naeem M (author)
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Fatima, Farah (author)
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Neder, Luciano (author)
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Kislinger, Thomas (author)
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(creator_code:org_t)
- 2014-11-18
- 2014
- English.
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In: Nature reviews. Urology. - : Springer Science and Business Media LLC. - 1759-4820 .- 1759-4812. ; 11, s. 688-701
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Abstract
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- The knowledge gained from comprehensive profiling projects that aim to define the complex genomic alterations present within cancers will undoubtedly improve our ability to detect and treat those diseases, but the influence of these resources on our understanding of basic cancer biology is still to be demonstrated. Extracellular vesicles have gained considerable attention in past years, both as mediators of intercellular signalling and as potential sources for the discovery of novel cancer biomarkers. In general, research on extracellular vesicles investigates either the basic mechanism of vesicle formation and cargo incorporation, or the isolation of vesicles from available body fluids for biomarker discovery. A deeper understanding of the cargo molecules present in extracellular vesicles obtained from patients with urogenital cancers, through high-throughput proteomics or genomics approaches, will aid in the identification of novel diagnostic and prognostic biomarkers, and can potentially lead to the discovery of new therapeutic targets.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Nawaz, Muhammad
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Camussi, Giovann ...
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Valadi, Hadi, 19 ...
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Nazarenko, Irina
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Ekström, Karin, ...
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Wang, Xiaoqin
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show more...
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Principe, Simona
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Shah, Neelam
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Ashraf, Naeem M
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Fatima, Farah
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Neder, Luciano
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Kislinger, Thoma ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dentistry
- Articles in the publication
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Nature reviews. ...
- By the university
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University of Gothenburg