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Biomarkers in demen...
Biomarkers in dementia: clinical utility and new directions
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Ahmed, R. M. (author)
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Paterson, R. W. (author)
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Warren, J. D. (author)
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- Zetterberg, Henrik, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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O'Brien, J. T. (author)
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Fox, N. C. (author)
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Halliday, G. M. (author)
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Schott, J. M. (author)
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(creator_code:org_t)
- 2014-09-26
- 2014
- English.
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In: Journal of Neurology Neurosurgery and Psychiatry. - : BMJ. - 0022-3050 .- 1468-330X. ; 85:12, s. 1426-1434
- Related links:
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https://jnnp.bmj.com...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Imaging, cerebrospinal fluid (CSF) and blood-based biomarkers have the potential to improve the accuracy by which specific causes of dementia can be diagnosed in vivo, provide insights into the underlying pathophysiology, and may be used as inclusion criteria and outcome measures for clinical trials. While a number of imaging and CSF biomarkers are currently used for each of these purposes, this is an evolving field, with numerous potential biomarkers in varying stages of research and development. We review the currently available biomarkers for the three most common forms of neurodegenerative dementia, and give an overview of research techniques that may in due course make their way into the clinic.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- FRONTOTEMPORAL LOBAR DEGENERATION
- MILD COGNITIVE IMPAIRMENT
- ALZHEIMERS
- ASSOCIATION WORKGROUPS
- PRIMARY-PROGRESSIVE-APHASIA
- POSITRON-EMISSION-TOMOGRAPHY
- CEREBROSPINAL-FLUID S100B
- VOXEL-BASED
- MORPHOMETRY
- LEWY BODIES
- BEHAVIORAL VARIANT
- CSF BIOMARKERS
Publication and Content Type
- ref (subject category)
- art (subject category)
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