Sympathetic nervous activation following subarachnoid hemorrhage: Influence of intravenous clonidine.

• Subarachnoid hemorrhage is often accompanied by systemic complications and cerebral vasospasm. Elevated levels of circulating catecholamines may be involved in the pathophysiology behind these events. The alpha-2-agonist clonidine inhibits sympathetic outflow by a central mechanism. Unrestricted sympathoexcitation may be detrimental and administration of clonidine may be beneficial in these patients.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)

Nyckelord

Adrenergic alpha-Agonists

pharmacology

Adult

Clonidine

administration & dosage

pharmacokinetics

pharmacology

Female

Hemodynamics

drug effects

Humans

Infusions

Intravenous

Male

Middle Aged

Norepinephrine

blood

Subarachnoid Hemorrhage

physiopathology

Sympathetic Nervous System

physiopathology

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)