Sökning: id:"swepub:oai:gup.ub.gu.se/242397" >
Blood fatty acid co...
Blood fatty acid composition in relation to allergy in children aged 2–9 years: results from the European IDEFICS study
-
- Mikkelsen, Andrea (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för folkhälsoepidemiologi,Institute of Medicine, Department of Public Health and Community Medicine, Public Health Epidemiology Unit,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Sect Epidemiol & Social Med, POB 453, S-40530 Gothenburg, Sweden / Närhalsan, Res & Dev Primary Hlth Care, Gothenburg, Region Västra G, Sweden
-
- Galli, Claudio (författare)
- Univ Milan, Dept Pharmacol & Biomol Sci, DiSFeB, Milan, Italy
-
- Eiben, Gabriele, 1960 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Sect Epidemiol & Social Med, POB 453, S-40530 Gothenburg, Sweden
-
visa fler...
-
- Ahrens, Wolfgang (författare)
- Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany
-
- Iacoviello, Lucia (författare)
- Dept Epidemiol & Prevent, Lab Mol & Nutrit Epidemiol, IRCCS Ist Neurol Mediterraneo Neuromed, Pozzilli, Italy
-
- Molnar, Denis (författare)
- Univ Pecs, Dept Pediat, Pecs, Hungary
-
- Pala, Valeria (författare)
- Dept Prevent & Predict Med, Epidemiol Unit, Fdn IRCCS Ist Nazl Tumori, Milan, Italy
-
- Rise, Patrizia (författare)
- Univ Milan, Dept Pharmacol & Biomol Sci, DiSFeB, Milan, Italy
-
- Rodriguez, Gerardo (författare)
- Univ Zaragoza, GENUD Growth Exercise Nutr & Dev, Res Grp, Zaragoza, Spain.;Inst Invest Sanitaria, Aragon, Spain
-
- Russo, Patrizia (författare)
- CNR, Inst Food Sci, Avellino, Italy
-
- Tornaritis, Michael (författare)
- Res & Educ Inst Child Hlth, Strovolos, Cyprus
-
- Veidebaum, Tomas (författare)
- Natl Inst Hlth Dev, Tallinn, Estonia
-
- Vyncke, Krishna (författare)
- Department of Public Health, University of Ghent, Ghent, Belgium
-
- Wolters, Maike (författare)
- Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany
-
- Mehlig, Kirsten, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för folkhälsoepidemiologi,Institute of Medicine, Department of Public Health and Community Medicine, Public Health Epidemiology Unit,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Sect Epidemiol & Social Med, POB 453, S-40530 Gothenburg, Sweden / Univ Ghent, Dept Publ Hlth, Ghent, Belgium
-
visa färre...
-
(creator_code:org_t)
- 2016-09-21
- 2017
- Engelska.
-
Ingår i: European Journal of Clinical Nutrition. - : Springer Science and Business Media LLC. - 0954-3007 .- 1476-5640. ; 71, s. 39-44
- Relaterad länk:
-
https://gup.ub.gu.se...
-
visa fler...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background/objectives: Blood polyunsaturated fatty acids (PUFA) are involved in allergy development, but the etiological role of n-6 and n-3 PUFA is still controversial. A European multicenter study of children (IDEFICS) provided the opportunity to explore the cross-sectional association between fatty acids (FA) and allergy. Subjects/methods: Blood FA levels were measured in 2600 children aged 2–9 years and were recorded as the percentage of weight of all FA detected. Logistic regression of allergy status on FA components was adjusted for age, sex, country, body mass index, family history of allergic disease, breast-feeding, and number of siblings. The results were given as odds ratios (OR) for current vs no allergy ever and an increase in FA by 1s.d. Results: Overall, higher proportions of n-6 PUFA were associated with higher odds of allergy (OR=1.21 (1.05, 1.40)). Monounsaturated FA (MUFA) were associated with reduced risk for allergy (OR=0.75 (0.65, 0.87)), whereas saturated FA did not differ by allergy status. The strongest associations were observed in children <4 years old, with ORs of allergy given as 1.62 (1.15, 2.29) for n-3 PUFA and 0.63 (0.42, 0.95) for MUFA. With regard to individual FA, these associations were independently observed for docosapentaenoic acid (22:5 n-3) and oleic acid (18:1 n-9). Conclusions: Both PUFA subtypes were positively associated with allergy in an age-dependent manner, whereas MUFA was associated with less allergy. The observation of high proportions of n-3 PUFA in allergic children younger than 4 years might help to understand the nature of early onset of atopic disease.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- allergy
- polyunsaturated fatty acids
- observational studies
- children
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Mikkelsen, Andre ...
-
Galli, Claudio
-
Eiben, Gabriele, ...
-
Ahrens, Wolfgang
-
Iacoviello, Luci ...
-
Molnar, Denis
-
visa fler...
-
Pala, Valeria
-
Rise, Patrizia
-
Rodriguez, Gerar ...
-
Russo, Patrizia
-
Tornaritis, Mich ...
-
Veidebaum, Tomas
-
Vyncke, Krishna
-
Wolters, Maike
-
Mehlig, Kirsten, ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Annan medicin oc ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Folkhälsovetensk ...
- Artiklar i publikationen
-
European Journal ...
- Av lärosätet
-
Göteborgs universitet
-
Högskolan i Skövde