Sökning: id:"swepub:oai:gup.ub.gu.se/251610" >
Is there evidence o...
Is there evidence of potential overtreatment of glycaemia in elderly people with type 2 diabetes? Data from the GUIDANCE study
-
Muller, N. (författare)
-
Khunti, K. (författare)
-
Kuss, O. (författare)
-
visa fler...
-
- Lindblad, Ulf, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
-
Nolan, J. J. (författare)
-
Rutten, Gehm (författare)
-
Trento, M. (författare)
-
Porta, M. (författare)
-
Roth, J. (författare)
-
Charpentier, G. (författare)
-
Jorgens, V. (författare)
-
Muller, U. A. (författare)
-
visa färre...
-
(creator_code:org_t)
- 2016-11-11
- 2017
- Engelska.
-
Ingår i: Acta Diabetologica. - : Springer Science and Business Media LLC. - 0940-5429 .- 1432-5233. ; 54:2, s. 209-214
- Relaterad länk:
-
https://gup.ub.gu.se...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- We used data from the GUIDANCE Study to determine the care of people with type 2 diabetes according to age and accompanying cardiovascular diseases and to assess indicators of overtreatment of glycaemia. The GUIDANCE study was a retrospective, cross-sectional study from 2009-2010 based on the records of 7597 people in France, Belgium, Italy, the Netherlands, Sweden, UK, Ireland and Germany. We analysed the level of metabolic control achieved and blood glucose-lowering medication used in different age groups and in relation to accompanying diseases. 4.459 patients (59.1%) were 65 years or older. Their HbA1c levels were similar to those with < 65 years. 44.7% of patients ae65 years had an HbA1c ae7% (53 mmol/mol) and were treated with insulin or sulfonylureas, and 27.1% of them had ischaemic heart disease or congestive heart failure. Significantly more patients with heart disease had HbA1c values ae7% (53 mmol/mol) and were treated more often with insulin or sulfonylureas compared to patients of the same age without heart disease. Most patients were treated according to guidelines valid at the time this large international patient sample was surveyed. Older and younger patients were at a similar level of metabolic control, and almost half of the patients with an age of ae65 years and treated with insulin or sulfonylurea had HbA1c levels below the target range (ae7%) for younger patients. However, these patients have an increased risk of severe hypoglycaemic events with potentially dangerous complications, particularly in those with cardiovascular diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Nyckelord
- Type 2 diabetes
- HbA1c
- Hypoglycaemia
- Overtreatment
- severe hypoglycemia
- glucose level
- older-adults
- mortality
- mellitus
- patient
- disease
- risk
- Endocrinology & Metabolism
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Muller, N.
-
Khunti, K.
-
Kuss, O.
-
Lindblad, Ulf, 1 ...
-
Nolan, J. J.
-
Rutten, Gehm
-
visa fler...
-
Trento, M.
-
Porta, M.
-
Roth, J.
-
Charpentier, G.
-
Jorgens, V.
-
Muller, U. A.
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Endokrinologi oc ...
- Artiklar i publikationen
-
Acta Diabetologi ...
- Av lärosätet
-
Göteborgs universitet