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Vitamin D intake du...
Vitamin D intake during the first 4years and onset of asthma by age 5: A nested case-control study.
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- Nwaru, Bright I, 1978 (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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Hadkhale, Kishor (författare)
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Hämäläinen, Niina (författare)
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Takkinen, Hanna-Mari (författare)
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Ahonen, Suvi (författare)
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Ilonen, Jorma (författare)
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Toppari, Jorma (författare)
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Niemelä, Onni (författare)
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Haapala, Anna-Maija (författare)
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Veijola, Riitta (författare)
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Knip, Mikael (författare)
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Virtanen, Suvi M (författare)
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(creator_code:org_t)
- 2017-09-08
- 2017
- Engelska.
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Ingår i: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. - : Wiley. - 1399-3038. ; , s. 1-8
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Early-life vitamin D intake has been linked to asthma risk in childhood, but the role of longitudinal vitamin D exposure has not been previously evaluated. We investigated the association between vitamin D intake during the first 4years of life and asthma risk by age 5.Within a Finnish population-based birth cohort, 182 incident asthma cases were matched to 728 controls on sex, genetic risk for type 1 diabetes, delivery hospital, and time of birth. Vitamin D intake was assessed by age-specific 3day food records. Parents completed a validated version of the International Study of Asthma and Allergies in Childhood questionnaire at 5years.At 3months, supplements were the main source of vitamin D intake; intake from foods increased from 3months on, mainly from fortified milk products. Vitamin D intake at each specific age was associated with an increased risk of any asthma, atopic, and non-atopic asthma, but only intake at 1 and 2years was statistically significantly associated with asthma. Longitudinal vitamin D intake was associated with an increased risk of asthma (OR 1.24; 95%CI 1.00-1.53).Increased vitamin D intake in childhood, particularly intake at 1 and 2years of age, may increase risk of childhood asthma. This might reflect a true effect or residual confounding by lifestyle or environmental factors. Repeated assessment of vitamin D intake allowed evaluation of the longitudinal and age-dependent impact of vitamin D on the risk of asthma. Further longitudinal studies are required to confirm or question these findings.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
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- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Nwaru, Bright I, ...
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Hadkhale, Kishor
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Hämäläinen, Niin ...
-
Takkinen, Hanna- ...
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Ahonen, Suvi
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Ilonen, Jorma
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visa fler...
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Toppari, Jorma
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Niemelä, Onni
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Haapala, Anna-Ma ...
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Veijola, Riitta
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Knip, Mikael
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Virtanen, Suvi M
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visa färre...
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Göteborgs universitet