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Culprit and Nonculp...
Culprit and Nonculprit Recurrent Ischemic Events in Patients with Myocardial Infarction: Data from SWEDEHEART (Swedish Web System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies)
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- Varenhorst, Christoph, 1977- (författare)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi,Uppsala Clin Res Ctr, Sweden; Uppsala Univ, Sweden
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- Hasvold, P. (författare)
- AstraZeneca Nord Baltic, Sodertalje, Sweden.;AstraZeneca R&D, Molndal, Sweden.,AstraZeneca Nord Baltic, Sweden; AstraZeneca RandD, Sweden
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- Johansson, S. (författare)
- Uppsala University Hospital,AstraZeneca R&D, Molndal, Sweden.,Uppsala Clin Res Ctr, Sweden; Uppsala Univ, Sweden; AstraZeneca RandD, Sweden
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- Janzon, Magnus (författare)
- Linköpings universitet,Linköping University,Linkoping Univ, Dept Cardiol, Linkoping, Sweden.;Linkoping Univ, Dept Med & Hlth Sci, Linkoping, Sweden.,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Albertsson, Per, 1956 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska Academy,Univ Gothenburg, Sahlgrenska Acad, Gothenburg, Sweden.
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- Leosdottir, Margret (författare)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Lund Univ, Dept Cardiol, Skane Univ Hosp, Malmo, Sweden.
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- Hambraeus, K. (författare)
- Falun Cty Hosp, Falun, Sweden.
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- James, Stefan, 1964- (författare)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi,Uppsala Clinical Research Center, Uppsala, Sweden; Uppsala University, Uppsala, Sweden
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- Jernberg, T. (författare)
- Karolinska Institutet,Solna Karolinska Univ Hosp, Sweden
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- Svennblad, Bodil (författare)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Ortopedi,Epihubben,Uppsala Clin Res Ctr, Sweden
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- Lagerqvist, Bo, 1952- (författare)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi,Uppsala Clin Res Ctr, Sweden; Uppsala Univ, Sweden
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(creator_code:org_t)
- WILEY, 2018
- 2018
- Engelska.
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Ingår i: Journal of the American Heart Association. - : WILEY. - 2047-9980. ; 7:1
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http://dx.doi.org/10... (free)
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://liu.diva-por... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background-Long-term disease progression after myocardial infarction (MI) is inadequately understood. We evaluated the pattern and angiographic properties (culprit lesion [CL]/non-CL [NCL]) of recurrent MI (re-MI) in a large real-world patient population. Methods and Results--Our observational study used prospectively collected data in 108 615 patients with first-occurrence MI enrolled in the SWEDEHEART (Swedish Web System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies) between July 1, 2006 and November 29, 2014. During follow-up (median, 3.2 years), recurrent hospitalization for MI occurred in 11 117 patients (10.2%). Of the patients who underwent coronary angiography for the index MI, a CL was identified in 44 332 patients. Of those patients, 3464 experienced an re-MI; the infarct originated from the NCL in 1243 patients and from the CL in 655 patients. In total, 1566 re-MIs were indeterminate events and could not be classified as NCL or CL re-MIs. The risk of re-MI within 8 years related to the NCL was 0.06 (95% confidence interval [CI], 0.05-0.06), compared with 0.03 (95% CI, 0.02-0.03) for the CL. There were no large differences in baseline characteristics of patients with subsequent NCL versus CL re-MIs. Independent predictors of NCL versus CL re- MI were multivessel disease (odds ratio, 2.29; 95% CI, 1.87-2.82), male sex (odds ratio, 1.36; 95% CI, 1.09-1.71), and a prolonged time between the index and re-MI (odds ratio, 1.16; 95% CI, 1.10- 1.22). Conclusions--In a large cohort of patients with first-occurrence MI undergoing percutaneous coronary intervention, the risk of re-MI originating from a previously untreated lesion was twice higher than the risk of lesions originating from a previously stented lesion.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Culprit artery
- Myocardial infarction
- Nonculprit artery
- Percutaneous coronary intervention
- Prognosis
- aged
- Article
- cardiovascular risk
- clinical feature
- controlled study
- coronary angiography
- evidence based medicine
- female
- follow up
- heart infarction
- hospitalization
- human
- incidence
- ischemia
- major clinical study
- male
- observational study
- prediction
- priority journal
- prospective study
- recurrent disease
- sex
- vascular disease
- culprit artery
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Varenhorst, Chri ...
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Hasvold, P.
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Johansson, S.
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Janzon, Magnus
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Albertsson, Per, ...
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Leosdottir, Marg ...
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Hambraeus, K.
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James, Stefan, 1 ...
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Jernberg, T.
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Svennblad, Bodil
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Lagerqvist, Bo, ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Journal of the A ...
- Av lärosätet
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Göteborgs universitet
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Lunds universitet
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Uppsala universitet
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Karolinska Institutet
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Linköpings universitet