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Coronary-artery byp...
Coronary-artery bypass surgery in patients with left ventricular dysfunction.
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Velazquez, Eric J (författare)
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Lee, Kerry L (författare)
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Deja, Marek A (författare)
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Jain, Anil (författare)
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Sopko, George (författare)
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Marchenko, Andrey (författare)
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Ali, Imtiaz S (författare)
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Pohost, Gerald (författare)
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Gradinac, Sinisa (författare)
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Abraham, William T (författare)
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- Bergh, Claes-Håkan, 1951 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Andersson, Bert, 1952 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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(creator_code:org_t)
- 2011
- 2011
- Engelska.
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Ingår i: The New England journal of medicine. - 1533-4406. ; 364:17, s. 1607-16
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The role of coronary-artery bypass grafting (CABG) in the treatment of patients with coronary artery disease and heart failure has not been clearly established.Between July 2002 and May 2007, a total of 1212 patients with an ejection fraction of 35% or less and coronary artery disease amenable to CABG were randomly assigned to medical therapy alone (602 patients) or medical therapy plus CABG (610 patients). The primary outcome was the rate of death from any cause. Major secondary outcomes included the rates of death from cardiovascular causes and of death from any cause or hospitalization for cardiovascular causes.The primary outcome occurred in 244 patients (41%) in the medical-therapy group and 218 (36%) in the CABG group (hazard ratio with CABG, 0.86; 95% confidence interval [CI], 0.72 to 1.04; P=0.12). A total of 201 patients (33%) in the medical-therapy group and 168 (28%) in the CABG group died from an adjudicated cardiovascular cause (hazard ratio with CABG, 0.81; 95% CI, 0.66 to 1.00; P=0.05). Death from any cause or hospitalization for cardiovascular causes occurred in 411 patients (68%) in the medical-therapy group and 351 (58%) in the CABG group (hazard ratio with CABG, 0.74; 95% CI, 0.64 to 0.85; P<0.001). By the end of the follow-up period (median, 56 months), 100 patients in the medical-therapy group (17%) underwent CABG, and 555 patients in the CABG group (91%) underwent CABG.In this randomized trial, there was no significant difference between medical therapy alone and medical therapy plus CABG with respect to the primary end point of death from any cause. Patients assigned to CABG, as compared with those assigned to medical therapy alone, had lower rates of death from cardiovascular causes and of death from any cause or hospitalization for cardiovascular causes. (Funded by the National Heart, Lung, and Blood Institute and Abbott Laboratories; STICH ClinicalTrials.gov number, NCT00023595.).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Aged
- Cardiovascular Diseases
- mortality
- Combined Modality Therapy
- Coronary Artery Bypass
- Coronary Artery Disease
- complications
- drug therapy
- surgery
- Female
- Heart Failure
- drug therapy
- etiology
- surgery
- Hospitalization
- Humans
- Intention to Treat Analysis
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Proportional Hazards Models
- Ventricular Dysfunction
- Left
- drug therapy
- etiology
- surgery
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Velazquez, Eric ...
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Lee, Kerry L
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Deja, Marek A
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Jain, Anil
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Sopko, George
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Marchenko, Andre ...
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visa fler...
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Ali, Imtiaz S
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Pohost, Gerald
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Gradinac, Sinisa
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Abraham, William ...
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Bergh, Claes-Håk ...
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Andersson, Bert, ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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The New England ...
- Av lärosätet
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Göteborgs universitet