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Cardiovascular resp...
Cardiovascular responses to clonidine in alcohol withdrawal: are they related to psychopathology and mental well-being?
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- Fahlke, Claudia, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology
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Berggren, U (författare)
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Balldin, J (författare)
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(creator_code:org_t)
- 2000
- 2000
- Engelska.
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Ingår i: Alcohol (Fayetteville, N.Y.). - 0741-8329. ; 21:3, s. 231-7
- Relaterad länk:
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https://gup.ub.gu.se...
Abstract
Ämnesord
Stäng
- The possible relationships between alpha-2-adrenoceptor function, as assessed by blood pressure, heart rate, and sedative responses to clonidine (CLON; 1.5 microg/kg, i.v.), and psychopathology and mental well-being were investigated in 19 patients with alcohol-dependence in the early withdrawal period (days 1 and 7). An age-matched control group was used (n=17). CLON-induced maximum reduction of systolic blood pressure was less day 1 in the alcohol-dependent patients compared to controls. CLON was found to induce less sedation at day 7 compared to day 1 and to controls. No relationships were seen between the parameters for alpha-2-adrenoceptor function and psychopathology and mental well-being. These findings suggest that CLON-induced changes in blood pressures and heart rate reflect the cardiovascular situation in alcohol withdrawal and not aspects of behavior.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- Adrenergic alpha-Agonists
- pharmacology
- Adult
- Affect
- drug effects
- Alcoholism
- blood
- physiopathology
- psychology
- Anxiety
- drug therapy
- Blood Pressure
- drug effects
- physiology
- Central Nervous System Depressants
- adverse effects
- Clonidine
- pharmacology
- Ethanol
- adverse effects
- Heart Rate
- drug effects
- physiology
- Humans
- Male
- Mental Disorders
- chemically induced
- Middle Aged
- Pain
- drug therapy
- Statistics
- Nonparametric
- Substance Withdrawal Syndrome
- blood
- psychology
- Wakefulness
- drug effects
- physiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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