Electrochemistry in and of the Fly Brain

• Studying brain function and neuronal communication has been always crucial due to the complexity of these systems. A great deal of technology and model systems have been developed to study this subject. Yet, very small invertebrate systems such as the fruit fly, Drosophila are excellent models and often have better defined and more easily manipulated genetics. This review focuses on invivo, ex vivo, and invitro measurements of biogenic amines by electrochemical techniques on the fly nervous system. The methods include capillary electrophoresis, fast scan cyclic voltammetry, and chronoamperometry have been used to study both larval and adult central nervous systems. Better understanding of brain function in model systems should aid in finding solutions to biological and bioanalytical challenges related to human brain function and also neurodegenerative disease.

Ämnesord

NATURVETENSKAP  -- Kemi -- Oorganisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Inorganic Chemistry (hsv//eng)

TEKNIK OCH TEKNOLOGIER  -- Medicinteknik -- Annan medicinteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Medical Engineering -- Other Medical Engineering (hsv//eng)

TEKNIK OCH TEKNOLOGIER  -- Annan teknik -- Övrig annan teknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Other Engineering and Technologies -- Other Engineering and Technologies not elsewhere specified (hsv//eng)

NATURVETENSKAP  -- Data- och informationsvetenskap -- Datavetenskap (hsv//swe)

NATURAL SCIENCES  -- Computer and Information Sciences -- Computer Sciences (hsv//eng)

Nyckelord

Drosophila

Electrochemical methods

Brain

FSCV

CE-EC

Chronoamperometry

central-nervous-system

drosophila-melanogaster

biogenic-amines

capillary-electrophoresis

dopamine transporter

fruit-fly

neurodegenerative disease

fluorescence detection

parkinsons-disease

drug discovery

Chemistry

Electrochemistry

Electrochemical methods

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