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Radiological assess...
Radiological assessment of local resectability status in patients with pancreatic cancer: Interreader agreement and reader performance in two different classification systems
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- Loizou, L. (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Duran, C. V. (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Axelsson, E. (författare)
- Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden; Uppsala Univ Hosp, Sweden
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- Andersson, Mats, 1954 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,Univ Gothenburg, Sweden
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- Keussen, I. (författare)
- Skane Univ Hosp, Sweden
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- Strinnholm, J. (författare)
- Umeå universitet,Diagnostisk radiologi,Umea Univ, Sweden
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- Bartholomä, Wolf (författare)
- Linköpings universitet,Institutionen för medicin och hälsa,Medicinska fakulteten,Region Östergötland, Röntgenkliniken i Linköping
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- Del Chiaro, M. (författare)
- Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Segersvard, R. (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Lundell, L. (författare)
- Karolinska Inst, Sweden
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- Kartalis, N. (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- Engelska.
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Ingår i: European Journal of Radiology. - : Elsevier BV. - 0720-048X .- 1872-7727. ; 106, s. 69-76
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objectives: To assess the interreader agreement and reader performance in the evaluation of patients with pancreatic cancer (PC) in two classification systems of local resectability status prior to initiation of therapy, namely the National Comprehensive Cancer Network (NCCN) and Karolinska classification system (KCS). Methods: In this ethics review board-approved retrospective study, six radiologists independently evaluated pancreatic CT-examinations of 30 patients randomly selected from a tertiary referral centre's multidisciplinary tumour board database. Based on well-defined criteria of tumour-vessel relationship, each patient was assigned to one of three NCCN and six KCS categories. We assessed the intraclass correlation coefficient (ICC) and compared the percentages of correct tumour classification of the six readers in both systems (Chi-square test; a P-value < 0.05 was considered significant). The standard of reference was a consensus evaluation of CT-examinations by three readers not involved in the image analysis. Results: The ICC for NCCN and KCS was 0.82 and 0.84, respectively (very strong agreement). The percentages of correct tumour classification at NCCN and KCS were 53-83% and 30-57%, respectively, with no statistically significant differences in the overall reader comparison per classification system. In pair-wise comparison between readers for NCCN/KCS, there were statistically significant differences between reader 5 vs. readers 4 (P = 0.012) and 3 (P = 0.045)/ reader 5 vs. reader 4 (P = 0.037). Conclusion: Interreader agreement in both PC classification systems is very strong. NCCN may be advantageous in terms of reader performance compared to KCS.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- Pancreatic ductal carcinoma
- Classification
- Blood vessels
- Diagnostic imaging
- Surgery
- vein resection
- portal-vein
- adenocarcinoma
- pancreaticoduodenectomy
- ct
- Radiology
- Nuclear Medicine & Medical Imaging
- Pancreatic ductal carcinoma
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Loizou, L.
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Duran, C. V.
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Axelsson, E.
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Andersson, Mats, ...
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Keussen, I.
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Strinnholm, J.
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visa fler...
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Bartholomä, Wolf
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Del Chiaro, M.
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Segersvard, R.
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Lundell, L.
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Kartalis, N.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Radiologi och bi ...
- Artiklar i publikationen
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European Journal ...
- Av lärosätet
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Göteborgs universitet
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Umeå universitet
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Karolinska Institutet
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Linköpings universitet