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C-band-positive dou...
C-band-positive double minutes have kinetochore proteins.
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- Wettergren, Yvonne, 1957 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för cell- och molekylärbiologi, genetik,Department of Cell and Molecular Biology, Genetics
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Arnason, U (författare)
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Haaf, T (författare)
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Levan, A (författare)
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Levan, G (författare)
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(creator_code:org_t)
- 2008-05-15
- 1995
- Engelska.
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Ingår i: Cytogenetics and cell genetics. - : S. Karger AG. - 0301-0171. ; 68:1-2, s. 54-6
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Double minutes (DMs) have been shown generally to lack centromeres. In the present paper we report on C-band-positive DMs in Colcemid-resistant SEWA cells. These DMs were heavily labeled after in situ hybridization with mouse major satellite DNA and, furthermore, reacted positively with antikinetochore antibodies. Upon antikinetochore antibody labeling, the immunofluorescent signals of some DMs were strong, indicating that they had functional centromeres.
Ämnesord
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Nyckelord
- Animals
- Autoantibodies
- blood
- CREST Syndrome
- blood
- immunology
- Centromere
- genetics
- Chromosome Banding
- Clone Cells
- DNA
- Satellite
- Demecolcine
- toxicity
- Drug Resistance
- Multiple
- genetics
- Humans
- Kinetochores
- physiology
- Metaphase
- Mice
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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