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A randomised trial ...
A randomised trial comparing two protocols for transrectal prostate repeat biopsy: six lateral posterior plus six anterior cores versus a standard posterior 12-core biopsy
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- Örtegren, Joakim (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Section of Urology, Department of Surgery, Växjö County Hospital, Växjö, Sweden; epartment of Urology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Växjö Central Hospital
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- Holmberg, Jan Tage (författare)
- Section of Urology, Department of Surgery, Växjö County Hospital, Växjö, Sweden; Section of Urology, Department of Surgery, Ljungby Hospital, Ljungby, Sweden,Växjö Central Hospital,Ljungby lasarett
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- Lekas, E. (författare)
- Section of Urology, Department of Surgery, Växjö County Hospital, Växjö, Sweden,Växjö Central Hospital
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Maria, S. (författare)
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- Martensson, S. (författare)
- Section of Urology, Department of Surgery, Växjö County Hospital, Växjö, Sweden; Section of Urology, Department of Surgery, Ljungby Hospital, Ljungby, Sweden,Ljungby lasarett,Växjö Central Hospital
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- Richthoff, Jonas (författare)
- Lund University,Lunds universitet,Ljungby lasarett
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- Sundqvist, Pernilla, 1973- (författare)
- Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Urology
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- Kjölhede, Henrik, 1981 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Department of Urology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Region Västra Götaland, Department of Urology , Sahlgrenska University Hospital, Gothenburg, Sweden,Växjö Central Hospital
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- Bratt, Ola, 1963 (författare)
- Lund University,Lunds universitet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Department of Urology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Region Västra Götaland, Department of Urology , Sahlgrenska University Hospital, Gothenburg, Sweden
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- Liedberg, Fredrik (författare)
- Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,Urology - urothelial cancer, Malmö,Lund University Research Groups,Skåne University Hospital
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- Mana, Sabah (författare)
- Section of Urology, Department of Surgery, Ljungby Hospital, Ljungby, Sweden,Ljungby lasarett
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(creator_code:org_t)
- 2019-06-17
- 2019
- Engelska.
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Ingår i: Scandinavian Journal of Urology. - : Medical Journals Sweden AB. - 2168-1805 .- 2168-1813. ; 53:4, s. 217-221
- Relaterad länk:
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http://dx.doi.org/10...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Objective: To test the hypothesis that a combination of 6 posterior and 6 anterior cores detects more cancer than 12 posterior cores at a repeat transrectal prostate biopsy in men who have had one previous benign systematic biopsy. Patients and methods: Three hundred and forty men with persistently raised serum PSA were randomly allocated 1:1 to either a standard 12-core biopsy (12 cores from the lateral peripheral zone through a side-fire biopsy canal) or an experimental 12-core biopsy protocol with 6 anterior cores through an end-fire biopsy canal and 6 cores from the lateral peripheral zone through a side-fire biopsy canal. All biopsies were obtained transrectally with ultrasound guidance. The primary endpoint was cancer detection. Secondary endpoints were detection of ISUP Grade Groups/Gleason Grade Group >= 2 cancer, total biopsy cancer length and complications leading to medical intervention. Results: Prostate cancer was detected in 42/168 men (25%) in the experimental biopsy group and in 36/172 (21%) in the standard biopsy group (p = 0.44). The corresponding proportions for Gleason score >= 7 were 12% and 7% (p = 0.14). Median total cancer length was 4 (inter quartile range [IQR] = 1.5 - 6) mm in the end-fire group and 3 (IQR = 1.3 - 7) mm in the side-fire group. Ten men in the end-fire group and three in the side-fire group had a medical intervention for biopsy-related complications (p = 0.05). Conclusion: The biopsy protocol that included six end-fire anterior cores did not detect more cancer and was associated with more complications.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Prostate cancer
- rebiopsy
- end-fire
- side-fire
- randomized
- anterior biopsies
- cancer detection rates
- template biopsies
- ultrasound probe
- multicenter
- accuracy
- tumors
- Urology & Nephrology
- Prostate cancer
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Örtegren, Joakim
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Holmberg, Jan Ta ...
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Lekas, E.
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Maria, S.
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Martensson, S.
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Richthoff, Jonas
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visa fler...
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Sundqvist, Perni ...
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Kjölhede, Henrik ...
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Bratt, Ola, 1963
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Liedberg, Fredri ...
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Mana, Sabah
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Urologi och njur ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
- Artiklar i publikationen
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Scandinavian Jou ...
- Av lärosätet
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Göteborgs universitet
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Örebro universitet
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Lunds universitet