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Ceftazidime and ren...
Ceftazidime and renal function.
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- Alestig, Kjell, 1931 (författare)
- Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine
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Trollfors, Birger, 1947 (författare)
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Andersson, Rune, 1951 (författare)
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- Olaison, Lars, 1949 (författare)
- Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine
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Suurküla, M (författare)
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Norrby, S R (författare)
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(creator_code:org_t)
- Oxford University Press (OUP), 1984
- 1984
- Engelska.
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Ingår i: The Journal of antimicrobial chemotherapy. - : Oxford University Press (OUP). - 0305-7453 .- 1460-2091. ; 13:2, s. 177-81
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Glomerular filtration rate (GFR) as measured by 51Chrome-EDTA clearance, decreased with a mean of 10 ml/min during therapy with ceftazidime 2 g bid in 16 patients with initial GFR of 30 to 110 ml/min. A significant increase in the excretion of urinary alanine aminopeptidase was also found. In another three patients with initial GFR of 17-22 ml/min increases in serum creatinine during therapy were noted. These observations indicate that ceftazidime should be used with caution in patients with impaired renal function and not be combined with nephrotoxic drugs until the safety of such combinations has been studied.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Adult
- Aged
- Bacterial Infections
- drug therapy
- Ceftazidime
- Cephalosporins
- toxicity
- Chromium Radioisotopes
- Edetic Acid
- Female
- Glomerular Filtration Rate
- drug effects
- Half-Life
- Humans
- Kidney
- drug effects
- Male
- Middle Aged
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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