Separation of non-collagenous proteins of bone formed in titanium implants: experimental study in the rabbit tibia, using a bone harvest chamber.

• The non-collagenous proteins of mature cortical rabbit bone and 3 wk old bone specimens formed in titanium implant bone harvest chambers, were separated by means of fine pressure liquid chromatography. It was found that a sufficient amount of bone could be obtained from five bone harvest chambers in five rabbits during a period of 15 wk. A different protein chromatographic pattern was found in bone grown in bone harvest chambers as compared to normal cortical bone from the same region. This indicates a difference in bone quality and shows that this implant design can be used for biochemical analysis of bone formed adjacent to a biomaterial.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Physiology (hsv//eng)

Nyckelord

Animals

Bone Development

physiology

Bone and Bones

analysis

Chromatography

Gel

Prostheses and Implants

Proteins

isolation & purification

Rabbits

Tibia

analysis

Titanium

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)