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Prenylated Flavonoi...
Prenylated Flavonoids from the Roots of Tephrosia rhodesica
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- Atilaw, Yoseph (author)
- Uppsala universitet,Organisk kemi,Uppsala Univ, Dept ChemUniv Nairobi, Dept Chem, Nairobi 3019700100, Kenya.
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- Muiva-Mutisya, L. (author)
- Univ Nairobi, Dept Chem, Nairobi 3019700100, Kenya.
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- Bogaerts, J. (author)
- Univ Antwerp, Dept Chem, B-2020 Antwerp, Belgium.
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- Duffy, S. (author)
- Griffith Univ, Griffith Inst Drug Discovery, Discovery Biol, Nathan, Qld 4111, Australia.
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- Valkonen, A. (author)
- Univ Jyvaskyla, Dept Chem, FI-40014 Jyvaskyla, Finland.
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- Heydenreich, M. (author)
- Univ Potsdam, Inst Chem, D-14476 Potsdam, Germany.
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- Avery, V. M. (author)
- Griffith Univ, Griffith Inst Drug Discovery, Discovery Biol, Nathan, Qld 4111, Australia.
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- Rissanen, K. (author)
- Univ Jyvaskyla, Dept Chem, FI-40014 Jyvaskyla, Finland.
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- Erdelyi, Mate, 1975 (author)
- Uppsala universitet,Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology,Organisk kemi,Univ Gothenburg, Dept Chem & Mol Biol, SE-41296 Gothenburg, Sweden.
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- Yenesew, A. (author)
- Univ Nairobi, Dept Chem, Nairobi 3019700100, Kenya.
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(creator_code:org_t)
- 2020-08-13
- 2020
- English.
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In: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 83:8, s. 2390-2398
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Abstract
Subject headings
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- Five new compounds-rhodimer (1), rhodiflavan A (2), rhodiflavan B (3), rhodiflavan C (4), and rhodacarpin (5)-along with 16 known secondary metabolites, were isolated from the CH2Cl2-CH3OH (1:1) extract of the roots of Tephrosia rhodesica. They were identified by NMR spectroscopic, mass spectrometric, X-ray crystallographic, and ECD spectroscopic analyses. The crude extract and the isolated compounds 2-5, 9, 15, and 21 showed activity (100% at 10 mu g and IC50 = 5-15 mu M) against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Keyword
- pterocarpan
- maackiain
- heartwood
- Plant Sciences
- Pharmacology & Pharmacy
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Atilaw, Yoseph
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Muiva-Mutisya, L ...
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Bogaerts, J.
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Duffy, S.
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Valkonen, A.
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Heydenreich, M.
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show more...
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Avery, V. M.
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Rissanen, K.
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Erdelyi, Mate, 1 ...
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Yenesew, A.
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Biochemistry and ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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and Organic Chemistr ...
- Articles in the publication
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Journal of Natur ...
- By the university
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University of Gothenburg
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Uppsala University