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Sexual orientation and adolescent suicide attempt and self-harm: a co-twin control study

O'Reilly, L. M. (författare)
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA
Pettersson, E. (författare)
Karolinska Institutet
Donahue, K. (författare)
Indiana University School of Medicine, Indianapolis, IN, USA
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Quinn, P. D. (författare)
Department of Applied Health Science, School of Public Health, Indiana University, Bloomington, IN, USA
Klonsky, E. D. (författare)
Department of Psychology, University of British Columbia, Vancouver, BC, Canada
Lundström, Sebastian (författare)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden
Larsson, Henrik, 1975- (författare)
Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Lichtenstein, P. (författare)
Karolinska Institutet
D'Onofrio, B. M. (författare)
Karolinska Institutet
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 (creator_code:org_t)
2020-09-14
2021
Engelska.
Ingår i: Journal of Child Psychology and Psychiatry. - : Wiley. - 0021-9630 .- 1469-7610. ; 62:7, s. 834-841
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Background Research has demonstrated that individuals who identify as a sexual minority (e.g., gay/lesbian, bisexual) are at increased risk for suicidality-related outcomes. However, previous research is primarily limited by the lack of adjustment for unmeasured (i.e., genetic and environmental) confounding factors and previous psychopathology. Methods Using the Child and Adolescent Twin Study in Sweden, we employed a co-twin control design to examine the extent to which the association between sexual orientation and adolescent suicide attempt and self-harm (SA/SH) was independent of genetic and environmental factors shared by twins, as well as measured symptoms of childhood psychopathology. Results Adolescents who identified as a sexual minority (i.e., gay/lesbian, bisexual, or other sexual orientation) were at two-fold increased odds for SA/SH (OR, 2.01 [95% confidence interval, 1.63-2.49) compared to heterosexual adolescents. When adjusting for all genetic and shared environmental factors that make twins similar and for measured childhood psychopathology, the association remained positive but attenuated to OR, 1.55 (1.11-2.16). Conclusions Identifying as a sexual minority was associated with approximately 50% increased odds of SA/SH in adolescence after adjusting for unmeasured genetic and environmental factors shared by twins and for childhood psychopathology. The results support that environmental factors specifically associated with identifying as a sexual minority likely increase risk for SA/SH. Our findings highlight the need to monitor suicidality risk among this group.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Nyckelord

Sexual behavior
suicidal behavior
twins
risk
minority
disparities
depression
behavior
ideation
health
youth
twin
Psychology
Psychiatry
Sexual behavior

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