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DHEA-S production c...
DHEA-S production capacity in relation to perceived prolonged stress
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Lennartsson, A. K. (författare)
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- Arvidson, Elin (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kost- och idrottsvetenskap,Department of Food and Nutrition, and Sport Science
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- Börjesson, Mats, 1965 (författare)
- Gothenburg University,Göteborgs universitet,Centrum för hälsa och prestationsutveckling,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Center for Health and Performance,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Jonsdottir, Ingibjörg H, 1966 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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(creator_code:org_t)
- 2022-01-17
- 2022
- Engelska.
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Ingår i: Stress - The International Journal on the Biology of Stress. - : Informa UK Limited. - 1025-3890. ; 25:1, s. 105-112
- Relaterad länk:
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- We and other research groups have previously described that levels of the anabolic hormone dehydroepiandrosterone sulfate (DHEA-S) are lowered in individuals who report prolonged stress. We have also shown that the DHEA-S production capacity during acute stress is attenuated in individuals reporting high prolonged stress. This study aimed to further investigate the DHEA and DHEA-S production capacity in relation to prolonged stress. Eighty-one healthy participants in the age 20-50 years old were included in the study and divided into a low stress (n = 45) and a high stress group (n = 36) according their response to a single question regarding perceived stress during the preceding month. They underwent the Trier Social Stress Test while blood samples were drawn before, during and after the stress test. The concentration of DHEA, DHEA-S, cortisol and ACTH was measured. The results showed that the high stress group exhibited a significantly lower response of DHEA-S (40% lower) than the low stress group, while DHEA, cortisol and ACTH responses did not differ between the groups. Reduced DHEA-S production may constitute one of the links between stress and poor health.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
Nyckelord
- Psychosocial stress
- prolonged stress
- DHEA-S
- DHEA
- cortisol
- TSST
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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