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The effect of a tig...
The effect of a tight control regime with monthly follow-up on remission rates and reported pain in early rheumatoid arthritis
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- Aronsson, Maria (author)
- Lund University,Lunds universitet,Spenshults artrit grupp,Forskargrupper vid Lunds universitet,Spenshults arthritis group,Lund University Research Groups,Capio Movement,Spenshult Research and Development Center
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Teleman, A. (author)
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- Bergman, Stefan (author)
- University of Gothenburg,Lund University,Lunds universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Spenshults artrit grupp,Forskargrupper vid Lunds universitet,Spenshults arthritis group,Lund University Research Groups,Spenshult Research and Development Center,Sahlgrenska Academy
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- Lindqvist, Elisabet (author)
- Lund University,Lunds universitet,Lund Arthritis Research Group (LARG),Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital,Spenshults artrit grupp,Spenshults arthritis group,Spenshult Research and Development Center
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- Forslind, Kristina (author)
- Lund University,Lunds universitet,Spenshults artrit grupp,Forskargrupper vid Lunds universitet,Spenshults arthritis group,Lund University Research Groups,Spenshult Research and Development Center
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Andersson, M. L. E. (author)
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(creator_code:org_t)
- 2022-08-12
- 2023
- English.
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In: Musculoskeletal Care. - : Wiley. - 1557-0681 .- 1478-2189. ; 21:1, s. 159-168
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Abstract
Subject headings
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- Objective: To determine whether a tight control (TC) regime with monthly consultations to the physician for the first 6 months, could increase remission rate and improve reported pain of patients with early rheumatoid arthritis (RA). Methods: In this single-centre, TC study, with monthly visits to the physician, a cohort of 100 patients with early RA was consecutively included. They were compared with a reference cohort of 100 patients from the same clinic that had been conventionally managed. The patients were followed for 2 years. Results: The patients in the TC cohort had lower 28- joints disease activity score (DAS28) at three, six, 12 and 24 months, compared with the conventionally managed cohort, p <= 0.001. At 12 months, 71% in the TC cohort versus 46% in the conventional cohort were in remission (DAS28 < 2.6) and at 24 months 68% versus 49% respectively, p < 0.05. The TC cohort reported less pain at three, six, 12 and 24 months, p < 0.001. Multiple logistical regression analyses adjusted for, respectively, age, disease duration, pharmacological treatment, DAS28 and visual analogue scale pain at inclusion, revealed that participation in the TC cohort had an independent positive association with remission at 12 and 24 months and with acceptable pain at 24 months. Conclusion: The intensive follow-up schedule for patients with early RA improved remission and led to improvement in reported pain and physical function. The positive effect of a TC regime in early disease may be due to increased empowerment, developed by meeting health professionals frequently.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Keyword
- early RA
- pain
- remission
- rheumatoid arthritis
- tight control
- disability
- therapy
- blind
- Rheumatology
Publication and Content Type
- ref (subject category)
- art (subject category)
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