UTERUS TRANSPLANTATION: In Transition from Experimental to Clinical Procedure

• Uterus transplantation (UTx) during the last decades has developed as a novel infertility treatment for absolute uterine factor infertility (AUFI) caused by absence of a functional uterus. After systematic animal research [1] over a decade, and involving rodents, domestic species, and non-human primates, the first clinical UTx trial was launched in 2013 [2]. This was a live donor (LD) UTx trial and one out of nine participating women gave birth to the world’s first UTx baby in September 2014 [3]. Since then, more than 10 clinical UTx trials have been initiated, with a mix between LD UTx and deceased donor (DD) UTx. Based on data from all registered ongoing trials and our personal experience, we describe plausible patient groups for UTx and cover different techniques of surgery and assisted reproduction in conjunction with UTx.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)

Publication and Content Type

vet (subject category)

kap (subject category)