Minor salivary gland secretion rates and immunoglobulin A in adults and the elderly.

• Previously published data are conflicting about the effect of various factors on secretions from minor salivary glands. The aim of the present study was to investigate the secretion rate from palatal, buccal, and labial glands, and to analyze the immunoglobulin A (IgA) concentrations in relation to age, gender, circulatory disease, diabetes, medication, smoking, and pregnancy. Resting and stimulated whole-saliva secretion rates, as well as IgA concentration in stimulated whole saliva, were also examined. One-hundred and forty two individuals (96 women and 46 men), 18-82 yr of age, participated. The results did not suggest any effect of aging on the secretion capacity of minor salivary glands, but the IgA concentration seemed to increase with age. Women had lower buccal and labial saliva secretion rates, and lower levels of IgA in buccal saliva, than men. For whole saliva, resting, but not stimulated, saliva secretion rates were reduced with age, and the secretion rate of stimulated whole saliva was lower in women than in men. The IgA concentration in buccal saliva showed a positive correlation with IgA in stimulated whole saliva, and the IgA concentration decreased with increased flow rate in both salivas.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Nyckelord

Adolescent

Adrenergic beta-Antagonists

pharmacology

Adult

Age Factors

Aged

Aged

80 and over

Aging

physiology

Antihypertensive Agents

pharmacology

Female

Humans

Immunoglobulin A

Secretory

analysis

Male

Middle Aged

Pregnancy

Regression Analysis

Saliva

chemistry

immunology

secretion

Salivary Glands

Minor

drug effects

secretion

Secretory Rate

drug effects

Sex Factors

Smoking

Publikations- och innehållstyp

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art (ämneskategori)