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Human minor and maj...
Human minor and major gland saliva proteins and ability to mediate Actinomyces naeslundii adherence.
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- Carlén, Anette, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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- Eliasson, Lars, 1940 (författare)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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- Aronsson, Gunilla, 1948 (författare)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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visa fler...
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- Birkhed, Dowen, 1946 (författare)
- Gothenburg University,Göteborgs universitet,Odontologiska institutionen,Institute of Odontology
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visa färre...
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(creator_code:org_t)
- Elsevier BV, 2004
- 2004
- Engelska.
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Ingår i: Archives of oral biology. - : Elsevier BV. - 0003-9969. ; 49:3, s. 177-81
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Bacteria-binding components and the ability to mediate bacterial adhesion to the tooth surface have been thoroughly studied in major salivary gland secretions. Our knowledge on the bacteria binding activity in minor gland saliva is, however, limited. In this study, proteins were examined in parallel in minor (palatal, buccal and labial) and major (parotid and submandibular/sublingual) salivary gland secretions in one subject using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting. The adherence of early colonizing Actinomyces naeslundii to pellicles formed from the secretions on hydroxyapatite beads was also examined. Amylase, IgA, proline-rich proteins and the high-molecular-weight glycoproteins, agglutinins, were detected in all saliva tested. Carbohydrate-reactive antibodies recognized the low-molecular weight mucin, MUC 7 in submandibular/sublingual saliva only. A. naeslundii strain 12104 adhered to all pellicles and especially to the buccal gland saliva pellicles. Strain LY7 adhered in highest numbers to the submandibular/sublingual saliva pellicles. It also bound in considerable numbers to parotid and palatal saliva pellicles but not to the ones formed from buccal and labial gland saliva. Our findings indicate that several bacteria-binding components are secreted in both minor and major gland saliva. The adherence-promoting ability of the various gland secretions differs, however.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- Actinomyces
- physiology
- Adult
- Bacterial Adhesion
- physiology
- Dental Deposits
- microbiology
- Drosophila Proteins
- analysis
- physiology
- Electrophoresis
- Polyacrylamide Gel
- Humans
- Male
- Saliva
- chemistry
- Salivary Glands
- secretion
- Salivary Glands
- Minor
- secretion
- Salivary Proteins
- analysis
- physiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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