Growth hormone and the cardiovascular function.

• In this review, the great importance of growth hormone (GH) for the maintenance of cardiac function in adult life is discussed. Physiological effects of GH are discussed as well as the cardiac dysfunction caused both by GH excess (acromegaly) and by GH deficiency in adult hypopituitary patients. In both acromegaly and adult GH deficiency, there is also increased cardiovascular morbidity and mortality. Finally, the effect of GH treatment in heart failure is discussed.

Nyckelord

Acromegaly

physiopathology

Animals

Cardiac Output

physiology

Growth Hormone

biosynthesis

deficiency

physiology

therapeutic use

Heart

physiology

physiopathology

Heart Diseases

drug therapy

physiopathology

Humans

Hypopituitarism

physiopathology

Insulin-Like Growth Factor I

physiology

Myocardium

metabolism

Treatment Outcome

Publikations- och innehållstyp

ref (ämneskategori)

for (ämneskategori)