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Expected Gene Order...
Expected Gene Order Distances and Model Selection in Bacteria
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- Dalevi, Daniel, 1974 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology,Department of Computing Science and Engineering, Chalmers University of Technology, Gothenburg
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- Eriksen, Niklas, 1974 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper, matematik,Department of Mathematical Sciences, Mathematics,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology,Department of Mathematical Sciences, Gothenburg University and Chalmers University of Technology, Gotenhburg
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(creator_code:org_t)
- Oxford, United Kingdom : Oxford University Press, 2008
- 2008
- Engelska.
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Ingår i: Bioinformatics. - Oxford, United Kingdom : Oxford University Press. - 1367-4803 .- 1367-4811. ; 24:11, s. 1332-1338
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Abstract
Ämnesord
Stäng
- Motivation: The evolutionary distance inferred from gene-order comparisons of related bacteria is dependent on the model. Therefore, it is highly important to establish reliable assumptions before inferring its magnitude. Results: We investigate the patterns of dotplots between species of bacteria with the purpose of model selection in gene-order problems. We find several categories of data which can be explained by carefully weighing the contributions of reversals, transpositions, symmetrical reversals, single gene transpositions and single gene reversals. We also derive method of moments distance estimates for some previously uncomputed cases, such as symmetrical reversals, single gene reversals and their combinations, as well as the single gene transpositions edit distance.
Ämnesord
- NATURVETENSKAP -- Matematik -- Diskret matematik (hsv//swe)
- NATURAL SCIENCES -- Mathematics -- Discrete Mathematics (hsv//eng)
- NATURVETENSKAP -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datavetenskap (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Sciences (hsv//eng)
Nyckelord
- reversal
- inversion
- transposition
- gene order rearrangement
- method of moments estimate
- inversion
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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