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Extinction of condi...
Extinction of conditioned blink responses by cerebello-olivary pathway stimulation
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- Bengtsson, Fredrik (författare)
- Lund University,Lunds universitet,Hjärnans sensorimotoriska funktioner,Forskargrupper vid Lunds universitet,Neural Basis of Sensorimotor Control,Lund University Research Groups
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- Jirenhed, Dan-Anders (författare)
- Lund University,Lunds universitet,Associativ inlärning,Forskargrupper vid Lunds universitet,Hjärnans sensorimotoriska funktioner,Associative Learning,Lund University Research Groups,Neural Basis of Sensorimotor Control
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- Svensson, Pär (författare)
- Lund University,Lunds universitet,Institutionen för experimentell medicinsk vetenskap,Medicinska fakulteten,Department of Experimental Medical Science,Faculty of Medicine
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- Hesslow, Germund (författare)
- Lund University,Lunds universitet,Associativ inlärning,Forskargrupper vid Lunds universitet,Associative Learning,Lund University Research Groups
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(creator_code:org_t)
- 2007
- 2007
- Engelska.
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Ingår i: NeuroReport. - 1473-558X. ; 18:14, s. 1479-1482
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Learning of classically conditioned eyeblink responses depends on mechanisms within the cerebellum. It has been suggested that climbing fibres from the inferior olive transmit the unconditioned stimulus signal to the cerebellum. We have previously shown that the pathway from the deep cerebellar nuclei to the inferior olive inhibits olivary activity. It is known that repeated presentation of the conditioned stimulus on its own leads to extinction of the conditioned response. If the unconditioned stimulus signal is transmitted to the cerebellum via the inferior olive - climbing fibre system then stimulation of the nucleo-olivary pathway just before the unconditioned stimulus in a trained animal should lead to extinction. The results from this investigation confirm this.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- extinction
- inferior olive
- unconditioned stimulus
- nucleo-olivary
- eyeblink conditioning
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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