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A new case of photo...
A new case of photoallergic contact dermatitis caused by benzophenones in magazine covers
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- Samaran, Quentin (författare)
- Montpellier University Hospital
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- Raison-Peyron, Nadia (författare)
- Montpellier University Hospital
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- Clark, Evangeline (författare)
- Montpellier University Hospital
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- Svedman, Cecilia (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Dahlin, Jakob (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Dereure, Olivier (författare)
- Montpellier University Hospital
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- Bruze, Magnus (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Bourrain, Jean Luc (författare)
- University of Montpellier,Montpellier University Hospital
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visa färre...
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(creator_code:org_t)
- 2022-02-13
- 2022
- Engelska 8 s.
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 86:4, s. 300-307
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Allergic contact dermatitis (ACD) and photoallergic contact dermatitis (PACD) to benzophenone present in printing ink have been reported. However, precise chemical analyses and extended photo-patch tests have not been performed in these cases. Objectives: To determine which components present in a magazine cover are responsible for a patient's skin reaction, to determine the primary sensitizer, and precisely diagnose ACD and PACD. Methods: After initial photo-patch tests were performed on a patient with a history of reaction to magazine covers after sun exposure, gas chromatography–mass spectrometry and high-performance liquid chromatography analyses of the magazine covers, and additional photo-patch tests were performed. Results: The first photo-patch test results confirmed PACD to ketoprofen and fenofibrate and evoked PACD to the magazine covers. 4-methyl benzophenone (4-MBP) and 1-hydroxy-cyclohexyl-phenyl-ketone (1-HCPK) were found in the magazine cover. Additional photo-patch tests confirmed PACD to 1-HCPK and to benzophenone, and photo-aggravated ACD to 4-MBP. The primary sensitizer was ketoprofen. Conclusions: Benzophenones are present in a wide variety of products, without always being listed on the packaging. Patients previously sensitized to other ketones, such as ketoprofen, may react to benzophenones without being able to avoid contact with these molecules. New regulations may be needed for more efficient eviction advice.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- 1-hydroxy-cyclohexyl-phenyl-ketone
- 4-methyl benzophenone
- CAS number 119-61-9
- CAS number 134-84-9
- CAS number 6197-30-4
- ketoprofen
- octocrylene
- photoallergy
- unsubstituted benzophenone
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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