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Effect of nanoparti...
Effect of nanoparticle size and magnetic field strength on the displacement signal in magnetomotive ultrasound imaging
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- Andersson, Roger (author)
- Skåne University Hospital
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- Evertsson, Maria (author)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Medicinsk teknik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,Biomedical Engineering, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Toftevall, Hanna (author)
- Genovis AB
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- Cinthio, Magnus (author)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH
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- Fredriksson, Sarah (author)
- Genovis AB
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- Jansson, Tomas (author)
- Skåne University Hospital
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(creator_code:org_t)
- 2016
- 2016
- English.
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In: 2016 IEEE International Ultrasonics Symposium, IUS 2016. - 9781467398978 ; 2016-November
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Abstract
Subject headings
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- Magnetomotive ultrasound imaging is an emerging technique where superparamagnetic iron oxide nanoparticles can be used as an ultrasound contrast agent. A time-varying external magnetic field acts to move tissue embedded particles, and ultrasound is used to detect the resulting tissue movement. In this experimental phantom study we observed a variation in the magnetomotive response in respect to physical size of the embedded superparamagnetic iron oxide nanoparticles. Given the same Fe concentration a weaker response, by a factor of 2, was detected with the larger nanoparticles. However, approximately seven times larger response remains, given the volume ratio between particles, implying a seven times larger response per binding event. We hypothesize that this can have bearing in molecular imaging.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- contrast agents
- iron oxide
- molecular imaging
- nanoparticles
- superparamagnetic
Publication and Content Type
- kon (subject category)
- ref (subject category)
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