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Pre-treatment dosim...
Pre-treatment dosimetry for interstitial photodynamic therapy
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- Johansson, Ann (författare)
- Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
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Hjelm, J (författare)
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Eriksson, A (författare)
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- Andersson-Engels, Stefan (författare)
- Lund University,Lunds universitet,Atomfysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Atomic Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
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(creator_code:org_t)
- SPIE, 2005
- 2005
- Engelska.
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Ingår i: Proceedings of the SPIE - The International Society for Optical Engineering. - : SPIE. - 1996-756X .- 0277-786X. ; 5863:1, s. 1-58630
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- A genetic algorithm for optimal placement of optical fibers in arbitrary geometries for interstitial photodynamic therapy has been developed. Based on calculated fiber positions, the diffuse light distribution is simulated by solving the diffusion equation by means of the finite element method and the treatment time is calculated. Utilizing an instrument for interstitial photodynamic therapy that is capable of both delivering the therapeutic irradiation and measuring parameters of relevance to treatment monitoring, knowledge has been gained on temporal variations of tissue light absorption, sensitizer photobleaching and tissue oxygenation status. We speculate on how variations in these three parameters can be implemented in a crude pre-treatment dosimetry model for photodynamic therapy
Ämnesord
- NATURVETENSKAP -- Fysik -- Atom- och molekylfysik och optik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Atom and Molecular Physics and Optics (hsv//eng)
Nyckelord
- tissue oxygenation
- sensitizer photobleaching
- tissue light absorption
- finite element method
- genetic algorithm
- dosimetry
- interstitial photodynamic therapy
Publikations- och innehållstyp
- kon (ämneskategori)
- ref (ämneskategori)
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