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Healthcare resource...
Healthcare resource utilization and device-aided therapy discussions with eligible patients across the Parkinson's disease continuum : Revelations from the MANAGE-PD validation cohort
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- Fernandez, Hubert H. (författare)
- Cleveland Clinic Foundation
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- Odin, Per (författare)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Restorative Parkinson Unit,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups
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Standaert, David G. (författare)
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- Henriksen, Tove (författare)
- Bispebjerg Hospital
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- Jimenez-shahed, Joohi (författare)
- Icahn School of Medicine at Mount Sinai
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Metz, Sharon (författare)
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- Alobaidi, Ali (författare)
- AbbVie Inc.
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- Yan, Connie H. (författare)
- AbbVie Inc.
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- Kukreja, Pavnit (författare)
- AbbVie Inc.
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- Parra, Juan Carlos (författare)
- AbbVie Inc.
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- Zamudio, Jorge (författare)
- AbbVie Inc.
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- Onuk, Koray (författare)
- AbbVie Inc.
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Wright, Jack (författare)
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- Antonini, Angelo (författare)
- University of Padova
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(creator_code:org_t)
- 2023
- 2023
- Engelska.
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Ingår i: Parkinsonism and Related Disorders. - 1353-8020. ; 116
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Introduction: Device-aided therapy may improve the quality of life (QoL) for people with advanced Parkinson's disease (PD) and poorly controlled symptoms with oral therapy. MANAGE-PD is a validated tool classifying patients based on symptom control and advanced treatment eligibility. This study focused on patient/caregiver reported outcomes and healthcare resource utilization among patients grouped by MANAGE-PD categories. Methods: Device-aided therapy-naïve patients receiving oral treatments were identified from the Adelphi Parkinson's Disease Programme. Patients were categorized (category 1 to 3) using MANAGE-PD. PD-specific QoL (PDQ-39), care partner burden (ZBI), satisfaction with current treatment, healthcare resource utilization, associated healthcare costs, and future treatment discussion with providers were measured. Categories were compared using ANOVA, t-test, chi square and adjusted regression analyses. Results: Of the analytical sample (n = 2709), 18.9% were inadequately controlled on current therapy and potentially eligible for device-aided therapies (category 3). As expected, they had worse patient/caregiver reported outcomes versus patients in categories 1 or 2. However, the degree of difference in healthcare resource utilization, including: greater number of hospitalizations, emergency room (ER) visits and consultations, higher likelihood of being recipients of respite care, and greater PD treatment burden, was unexpected. Importantly, of patients in category 3 and their care partners, >40% did not report discussions with providers about device-aided therapies. Conclusion: MANAGE-PD category 3 patients had significantly higher burden on healthcare resources versus patients well-controlled with oral treatment or requiring only oral medication adjustments; yet almost half had no discussion on device-aided therapies with providers. Device-aided therapies may be considered in these patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Device-aided therapy
- Healthcare resource utilization
- MANAGE-PD
- Parkinson's disease
- Quality of life
- Symptom control
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Fernandez, Huber ...
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Odin, Per
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Standaert, David ...
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Henriksen, Tove
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Jimenez-shahed, ...
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Metz, Sharon
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visa fler...
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Alobaidi, Ali
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Yan, Connie H.
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Kukreja, Pavnit
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Parra, Juan Carl ...
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Zamudio, Jorge
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Onuk, Koray
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Wright, Jack
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Antonini, Angelo
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
- Artiklar i publikationen
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Parkinsonism and ...
- Av lärosätet
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Lunds universitet