Search for the human papillomavirus in nasal polyps, using a polymerase chain reaction-method

• Viral etiology of nasal polyps was postulated as many as 40 years ago, but so far, no study has shown an association or causal relation between any specific virus and nasal polyps. By using the polymerase chain reaction (PCR) technique, nasal polyps from both 10 patients with intolerance to nonsteroidal anti-inflammatory drugs (NSAID intolerance) (e.g., Aspirin) and from 10 patients with no history of NSAID intolerance were studied for the presence of papillomavirus DNA. Nasal mucosa from 10 patients who had undergone surgery for septoplasty served as controls. The PCR test used covers approximately 30 different types of human papillomaviruses. In this test, all tissue samples studied were found negative for papillomavirus DNA.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Oto-rhino-laryngologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Otorhinolaryngology (hsv//eng)

Nyckelord

Adult

Aged

Anti-Inflammatory Agents, Non-Steroidal/adverse effects

Asthma/complications

DNA, Viral/analysis

Drug Hypersensitivity/complications

Female

Gene Amplification

Humans

Male

Middle Aged

Nasal Mucosa/virology

Nasal Polyps/virology

Nasal Septum/surgery

Papillomaviridae/genetics

Papillomavirus Infections/diagnosis

Polymerase Chain Reaction

Rhinoplasty

Tumor Virus Infections/diagnosis

Publikations- och innehållstyp

art (ämneskategori)

ref (ämneskategori)