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Advanced Imaging in...
Advanced Imaging in the Diagnosis and Response Assessment of High-Grade Glioma : AJR Expert Panel Narrative Review.
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- Hu, Leland S (författare)
- Mayo Clinic Scottsdale-Phoenix, Arizona
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- Smits, Marion (författare)
- Erasmus University Medical Center,Medical Delta
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- Kaufmann, Timothy J (författare)
- Mayo Clinic Minnesota
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- Knutsson, Linda (författare)
- Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,MR Physics,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Johns Hopkins University,Kennedy Krieger Institute
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- Rapalino, Otto (författare)
- Massachusetts General Hospital,Harvard Medical School
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- Galldiks, Norbert (författare)
- Jülich Research Centre,University of Cologne
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- Sundgrene, Pia C (författare)
- Lund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund University Bioimaging Center,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
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- Cha, Soonmee (författare)
- University of California, San Francisco
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(creator_code:org_t)
- Engelska.
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Ingår i: American Journal of Roentgenology: diagnostic imaging and related sciences. - 1546-3141.
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- This AJR Expert Panel Narrative explores the current status of advanced MRI and PET techniques for the post-therapeutic response assessment of high-grade adult-type gliomas, focusing on ongoing clinical controversies in current practice. Discussed techniques that complement conventional MRI and aid the differentiation of recurrent tumor from post-treatment effects include DWI and diffusion tensor imaging; perfusion MRI techniques including dynamic susceptibility contrast (DSC), dynamic contrast-enhanced MRI, and arterial spin labeling; MR spectroscopy including assessment of 2-hydroxyglutarate (2HG) concentration; glucose- and amino acid (AA)-based PET; and amide proton transfer imaging. Updated criteria for Response Assessment in Neuro-Oncology are presented. Given the abundant supporting clinical evidence, the panel supports a recommendation that routine response assessment after HGG treatment should include perfusion MRI, particularly given the development of a consensus recommended DSC-MRI protocol. Although published studies support 2HG MRS and AA PET, these techniques' widespread adoption will likely require increased availability (for 2HG MRS) or increased insurance funding in the United States (for AA PET). The article concludes with a series of consensus opinions from the author panel, centered on the clinical integration of the advanced imaging techniques into posttreatment surveillance protocols.
Ämnesord
- NATURVETENSKAP -- Annan naturvetenskap -- Övrig annan naturvetenskap (hsv//swe)
- NATURAL SCIENCES -- Other Natural Sciences -- Other Natural Sciences not elsewhere specified (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
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