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Twenty years on fro...
Twenty years on from the introduction of the high risk strategy for stroke and cardiovascular disease prevention : a systematic scoping review
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- Feigin, Valery L. (författare)
- Auckland University of Technology,University of Washington, Seattle
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- Martins, Sheila C. (författare)
- Hospital Moinhos de Vento
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- Brainin, Michael (författare)
- Danube University Krems
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- Norrving, Bo (författare)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk strokeforskning,Forskargrupper vid Lunds universitet,Stroke policy och kvalitetsregisterforskning,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Stroke Research Group,Lund University Research Groups,Stroke policy and quality register research,Skåne University Hospital
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- Kamenova, Saltanat (författare)
- Kazakh National Medical University
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- Giniyat, Azhar (författare)
- Ministry of Healthcare and Social Development, Kazakhstan
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- Kondybayeva, Aida (författare)
- Kazakh National Medical University
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- Aldyngurov, Daulet K. (författare)
- Ministry of Healthcare and Social Development, Kazakhstan
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- Bapayeva, Magripa (författare)
- Kazakh National Medical University
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- Zhanuzakov, Murat (författare)
- Al Farabi Kazakh National University
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- Hankey, Graeme J. (författare)
- University of Western Australia, Perth
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(creator_code:org_t)
- 2023
- 2023
- Engelska.
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Ingår i: European Journal of Neurology. - 1351-5101.
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background and purpose: Early this century, the high risk strategy of primary stroke and cardiovascular disease (CVD) prevention for individuals shifted away from identifying (and treating, as appropriate) all at-risk individuals towards identifying and treating individuals who exceed arbitrary thresholds of absolute CVD risk. The public health impact of this strategy is uncertain. Methods: In our systematic scoping review, the electronic databases (Scopus, MEDLINE, Embase, Google Scholar, Cochrane Library) were searched to identify and appraise publications related to primary CVD/stroke prevention strategies and their effectiveness published in any language from January 1990 to August 2023. Results: No published randomized controlled trial was found on the effectiveness of the high CVD risk strategy for primary stroke/CVD prevention. Targeting high CVD risk individuals excludes a large proportion of the population from effective blood-pressure-lowering and lipid-lowering treatment and effective CVD prevention. There is also evidence that blood pressure lowering and lipid lowering are beneficial irrespective of blood pressure and cholesterol levels and irrespective of absolute CVD risk and that risk-stratified pharmacological management of blood pressure and lipids to only high CVD risk individuals leads to significant underuse of blood-pressure-lowering and lipid-lowering medications in individuals otherwise eligible for such treatment. Conclusions: Primary stroke and CVD prevention needs to be done in all individuals with increased risk of CVD/stroke. Pharmacological management of blood pressure and blood cholesterol should not be solely based on the high CVD risk treatment thresholds. International guidelines and global strategies for primary CVD/stroke prevention need to be revised.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- cardiovascular disease
- high risk strategy
- prevention
- stroke
- trials
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- for (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Feigin, Valery L ...
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Martins, Sheila ...
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Brainin, Michael
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Norrving, Bo
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Kamenova, Saltan ...
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Giniyat, Azhar
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visa fler...
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Kondybayeva, Aid ...
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Aldyngurov, Daul ...
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Bapayeva, Magrip ...
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Zhanuzakov, Mura ...
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Hankey, Graeme J ...
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visa färre...
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och Klinisk medicin
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och Neurologi
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