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Sökning: id:"swepub:oai:lup.lub.lu.se:5f0e2914-003f-41d0-810c-35f733a7beb1" > Late cardiac events...

Late cardiac events after childhood cancer : Methodological aspects of the pan-european study pancaresurfup

Feijen, Elizabeth A M (författare)
Academic Medical Center of University of Amsterdam (AMC)
Font-Gonzalez, Anna (författare)
Academic Medical Center of University of Amsterdam (AMC)
Van Dalen, Elvira C. (författare)
Academic Medical Center of University of Amsterdam (AMC)
visa fler...
Van Der Pal, Helena J H (författare)
Academic Medical Center of University of Amsterdam (AMC)
Reulen, Raoul C. (författare)
Academic Medical Center of University of Amsterdam (AMC)
Winter, David L. (författare)
Academic Medical Center of University of Amsterdam (AMC)
Kuehni, Claudia E. (författare)
University of Bern
Haupt, Riccardo (författare)
Gaslini Children's Hospital
Alessi, Daniela (författare)
Citta' della Salute e della Scienza Hospital-University of Turin
Byrne, Julianne (författare)
Boyne Research Institute
Bardi, Edit (författare)
Semmelweis University
Jakab, Zsuzsanna (författare)
Markusovszky Hospital
Grabo, Desiree (författare)
Universitätsmedizin Mainz
Garwicz, Stanislaw (författare)
Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Sena effekter efter barncancerbehandling,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Late effects after childhood cancer treatment,Lund University Research Groups
Jankovic, Momcilo (författare)
University of Milano-Bicocca
Levitt, Gill A. (författare)
Great North Children's Hospital
Skinner, Roderick (författare)
University of Newcastle upon Tyne
Zaletel, Lorna Zadravec (författare)
Institute of Oncology, Ljubljana
Hjorth, Lars (författare)
Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Sena effekter efter barncancerbehandling,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Late effects after childhood cancer treatment,Lund University Research Groups
Tissing, Wim J E (författare)
University of Groningen
De Vathaire, Florent (författare)
Institut Gustave Roussy
Hawkins, Mike M. (författare)
University of Birmingham
Kremer, Leontien C M (författare)
Academic Medical Center of University of Amsterdam (AMC)
visa färre...
 (creator_code:org_t)
2016-09-19
2016
Engelska.
Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 11:9
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background and Aim Childhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup. Methods Eight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors. Data onsymptomatic heart failure, ischemia, pericarditis, valvular disease and arrhythmia were collected and graded according to the Criteria for Adverse Events. Detailed treatment data, data on potential confounders, lifestyle related risk factors and general health problems were collected. Results The PanCareSurFup cardiac cohort consisted of 59,915 5-year childhood cancer survivors with malignancies diagnosed between 1940 and 2009 and classified according to the International Classification of Childhood Cancer 3. Different strategies were used to identify cardiac events such as record linkage to population/ hospital or regional based databases, and patient-And general practitioner-based questionnaires. Conclusion The cardiac study of the European collaborative research project PanCareSurFup will provide the largest cohort of 5-year childhood cancer survivors with systematically ascertained and validated data on symptomatic cardiac events. The result of this study can provide information to minimize the burden of cardiac events in childhood cancer survivors by tailoring the follow-up of childhood cancer survivors at high risk of cardiac adverse events, transferring this knowledge into evidence-based clinical practice guidelines and providing a platformfor future research studies in childhood cancer patients.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

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