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Three variants of t...
Three variants of the leukotoxin gene in human isolates of Fusobacterium necrophorum subspecies funduliforme
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- Holm, Karin (author)
- Lund University,Lunds universitet,Infektionsmedicin,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Infection Medicine (BMC),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Collin, Mattias (author)
- Lund University,Lunds universitet,Infektionsmedicin,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Infektion och immunmodulering,Forskargrupper vid Lunds universitet,Infection Medicine (BMC),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Infection and immunomodulation,Lund University Research Groups
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- Hagelskjær-Kristensen, Lena (author)
- Viborg Regional Hospital
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- Jensen, Anders (author)
- Aarhus University
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- Rasmussen, Magnus (author)
- Lund University,Lunds universitet,Infektionsmedicin,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Infection Medicine (BMC),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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(creator_code:org_t)
- Elsevier BV, 2017
- 2017
- English.
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In: Anaerobe. - : Elsevier BV. - 1075-9964. ; 45, s. 129-132
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Abstract
Subject headings
Close
- Leukotoxin is a well-known virulence factor of animal isolates of Fusobacterium necrophorum subspecies necrophorum, and is also expressed by animal isolates of subspecies funduliforme, whereas its presence in isolates from humans has not been fully established. In this study we found that the leukotoxin gene was present in all tested F. necrophorum isolates from humans. Three sequence variants were found, two of which have not been described previously. The sequence types correlated to source of infection. Further studies are needed to examine the role of the leukotoxin in human infections.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- Fusobacterium necrophorum
- Lemierre
- Leukocidin
- Leukotoxin
- Pharyngotonsillitis
- Sequencing
Publication and Content Type
- art (subject category)
- ref (subject category)
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