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Predominance of cau...
Predominance of caudate nucleus lesions in acute ischemic stroke patients with impairments in language and speech
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Grönholm, Erik (författare)
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- Roll, Mikael (författare)
- Lund University,Lunds universitet,Allmän språkvetenskap,Avdelningen för lingvistik och kognitiv semiotik,Sektion 6,Språk- och litteraturcentrum,Institutioner,Humanistiska och teologiska fakulteterna,General Linguistics,Division of Linguistics and Cognitive Semiotics,Section 6,Centre for Languages and Literature,Departments,Joint Faculties of Humanities and Theology
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- Horne, Merle (författare)
- Lund University,Lunds universitet,Allmän språkvetenskap,Avdelningen för lingvistik och kognitiv semiotik,Sektion 6,Språk- och litteraturcentrum,Institutioner,Humanistiska och teologiska fakulteterna,General Linguistics,Division of Linguistics and Cognitive Semiotics,Section 6,Centre for Languages and Literature,Departments,Joint Faculties of Humanities and Theology
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- Sundgren, Pia (författare)
- Lund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Lindgren, Arne (författare)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk strokeforskning,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Stroke Research Group,Lund University Research Groups
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(creator_code:org_t)
- 2015-08-12
- 2016
- Engelska.
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Ingår i: European Journal of Neurology. - : Wiley. - 1351-5101 .- 1468-1331. ; 23:1, s. 148-153
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Abstract
Ämnesord
Stäng
- Background and purpose. Whereas traditional views of language processing in the brain have assumed that the language function is concentrated to a limited number of cortical areas (Broca’s and Wernicke’s areas), current knowledge points at a much more complex system of language and speech processing involving many brain areas, both cortical and subcortical. The purpose of the current study was to make an unbiased assessment of which cerebral areas are affected in first-ever acute ischemic stroke patients identified as having language and speech impairments according to the National Institute of Health Stroke Scale (NIHSS). Methods. Data from thirty-four patients with language and speech impairments, with a score of 1-3 on item 9 on the NIHSS, following ischemic stroke was collected from the Lund Stroke Register. MRI images acquired up to 20 days after stroke onset were used to create an overlap lesion image using MRIcron software. Results. The classical language areas, Wernicke’s and Broca’s area, were affected in less than one fourth of the patients. The most frequently affected region was a subcortical region - the left caudate nucleus and the adjacent corona radiata. Conclusions. These findings contribute to the growing body of evidence that the basal ganglia have a crucial role in the control over language and speech processing.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- HUMANIORA -- Språk och litteratur -- Jämförande språkvetenskap och allmän lingvistik (hsv//swe)
- HUMANITIES -- Languages and Literature -- General Language Studies and Linguistics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- caudate nucleus
- stroke
- speech
- language
- MRI
- basal ganglia
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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