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Influence of alpha-...
Influence of alpha-ketoglutarate on bone mineral density of the femur in piglets
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Kowalik, S (author)
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Filip, RS (author)
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Sliwa, E (author)
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Tatara, MR (author)
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- Pierzynowski, Stefan (author)
- Lund University,Lunds universitet,Funktionell zoologi,Biologiska institutionen,Naturvetenskapliga fakulteten,Functional zoology,Department of Biology,Faculty of Science
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Studzinski, T (author)
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(creator_code:org_t)
- 2005
- 2005
- English.
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In: Bulletin of the Veterinary Institute in Puławy. - 0042-4870. ; 49:3, s. 343-348
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http://www.piwet.pul... (free)
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Abstract
Subject headings
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- The aim of this study was to determine the influence of daily oral administration of alpha-ketoglutarate (AKG) on bone mineral density of the femur and concentration of 17-beta-oestradiol in blood plasma during 70 d of postnatal life in piglets. All the animals were kept under standard rearing conditions. AKG was administered orally from the 1(st) d of life, while the control piglets were treated in the same way and time with physiological saline. The experimental and control groups were assigned to 6 age subgroups: 3, 14, 21, 35, 56 and 70 d of life. The animals from both groups were euthanised, then bone samples were collected and frozen at -25 degrees C until further analyses. Using dual-energy x-ray absorptiometry (DEXA method) bone mineral density of the femora was estimated. Additionally, 17-beta-oestradiol concentration in blood plasma was assayed using RIA-test. The obtained results indicate positive influence of enteral AKG administration on bone mineral density of the femur in piglets. Moreover, AKG increased the level of 17-beta-oestradiol in blood plasma in post-weaned piglets.
Subject headings
- NATURVETENSKAP -- Biologi -- Zoologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Zoology (hsv//eng)
Keyword
- 17-beta-oestradiol
- bone mineral density
- femur
- piglets
- alpha-ketoglutarate
Publication and Content Type
- art (subject category)
- ref (subject category)
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