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Standardization of ...
Standardization of the TRUE Test imidazolidinyl urea and diazolidinyl urea patches
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Agner, T (författare)
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Andersen, K E (författare)
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Björkner, B (författare)
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- Bruze, Magnus (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups
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Frosch, P J (författare)
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Gruvberger, B (författare)
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Hoeck, U (författare)
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Kreilgaard, B (författare)
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Menne, T (författare)
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Sommer, J (författare)
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(creator_code:org_t)
- 2001-12-20
- 2001
- Engelska.
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873. ; 45:1, s. 21-25
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The preservatives imidazolidinyl urea (IMID, Germall 115) and diazolidinyl urea (DU, Germall II) are commonly used in cosmetic products and are well-known sensitizers. The aim of the present study was to establish the optimal patch test concentration in hydrophilic dried-in vehicle (TRUE Test) for IMID and DU. 181 patients were included in the study. Of these, 150 were patients referred for patch testing, 12 were patients with known allergy to IMID and 19 were patients with known allergy to DU. 76 consecutive patients and the 12 IMID-allergic patients were patch tested with a dilution series IMID (0 to 600 microg/cm(2)), formaldehyde (180 microg/cm(2)) and DU (200 microg/cm(2)). 74 consecutive patients and the 19 DU-allergic patients were patch tested with a dilution series of DU (0 to 600 microg/cm(2)), formaldehyde (180 microg/cm) and IMID (200 microg/cm(2)). A positive dose-response relationship was found. The number of doubtful reactions decreased with increasing test concentrations. No late reactions were observed. A patch test concentration in hydrophilic dried-in vehicle (TRUE Test) of 600 microg/cm(2) was found to be adequate and safe for both IMID and DU.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- imidazolidinyl urea
- Germall 115
- diazolidinyl urea
- Germall II
- TRUE Test
- formaldehyde
- dose-response
- concomitant reaction
- allergic contact dermatitis
- contact allergy
- patch testing technique
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Agner, T
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Andersen, K E
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Björkner, B
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Bruze, Magnus
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Frosch, P J
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Gruvberger, B
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visa fler...
-
Hoeck, U
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Kreilgaard, B
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Menne, T
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Sommer, J
-
visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Dermatologi och ...
- Artiklar i publikationen
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Contact Dermatit ...
- Av lärosätet
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Lunds universitet