Campylobacter infections with and without bacteraemia- a comparative retrospective population-based study

• BackgroundBacteraemia with species in the genus Campylobacter is rare, and knowledge of the disease course in comparison to Campylobacter enteritis is limited.MethodsThis is a retrospective population-based study. Episodes of Campylobacter bacteraemia, and Campylobacter enteritis with a concurrent negative blood culture, that occurred between 2015 and 2022 in southern Sweden were identified through the laboratory database. Medical records were reviewed and clinical features between patients with bacteraemic Campylobacter infections were compared with patients with Campylobacter spp. found in faeces.ResultsA total of 29 bacteraemic infections with Campylobacter and 119 patients with Campylobacter spp. found in faeces were included. Patients with Campylobacter bacteraemia were statistically significantly older compared to patients with only enteritis (72 years, IQR 58-62 years, and 58 years, IQR 33-67 years, respectively, p < 0.0001). Eleven patients with bacteraemia developed sepsis within 48 hours from blood culturing and no patient died within 30 days from hospital admission.ConclusionsCampylobacter bacteraemia is rare and occurs mainly in the elderly with co-morbidities. In comparison to Campylobacter infections limited to the gastrointestinal tract, patients with bacteraemic Campylobacter infections are older and seem more prone to develop sepsis. Classical gastroenteritis symptoms in bacteraemic patients with Campylobacter may be absent.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

Nyckelord

bacteremia

Campylobacter

enteritis

outcome

Publikations- och innehållstyp

art (ämneskategori)

ref (ämneskategori)