Predicting Nocturnal Hypoglycemia Using a Non-Parametric Insulin Action Model

• Nocturnal hypoglycemia is a common and potentially very dangerous condition facing persons with insulin-treated diabetes. To reduce the risk of going low while sleeping, many patient wilfully elevate their glucose level before bedtime, thereby also eroding the conditions for a sound glucose control for the next day. Recent advances in sensor technology allow for real-time frequent monitoring of the glucose level, and the road map towards an artificial pancreas involves combining an insulin pump with such sensors. The first steps towards a more autonomous insulin pump have been taken by allowing the pump to suspend the insulin supply when a hypoglycemic episode is imminent. This feature relies on algorithms for predicting the nocturnal event. In this paper, we present a novel model for this purpose. In comparison to previous methods, a better trade-off between sensitivity and false alarm rate was achieved, as well as improved warning time.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Reglerteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Control Engineering (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)

Nyckelord

Diabetes

non-parametric model

prediction

Publikations- och innehållstyp

kon (ämneskategori)

ref (ämneskategori)