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Synthesis and chara...
Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity
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Shi, W (författare)
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Liu, Y (författare)
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Liu, B (författare)
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Song, YG (författare)
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Xu, YK (författare)
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Wang, HM (författare)
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Sha, YL (författare)
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Xu, GZ (författare)
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- Styring, Stenbjörn (författare)
- Lund University,Lunds universitet,Biokemi och Strukturbiologi,Centrum för Molekylär Proteinvetenskap,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Biochemistry and Structural Biology,Center for Molecular Protein Science,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
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Huang, P (författare)
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(creator_code:org_t)
- 2007-01-25
- 2006
- Engelska.
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Ingår i: Journal of Coordination Chemistry. - : Informa UK Limited. - 1026-7441 .- 0095-8972 .- 1029-0389. ; 59:2, s. 119-130
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed.
Ämnesord
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Nyckelord
- 2-dimethyl-3
- 4-dihydro-2H-pyrrole-1-oxide
- spin trap
- pyrogallol
- autoxidation
- 2
- superoxide ion reactivity
- superoxide dismutase
- structure
- X-ray
- pyridine
- Manganese(III)
- 2-o-hydroxyphenylbenzimidazole
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Shi, W
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Liu, Y
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Liu, B
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Song, YG
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Xu, YK
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Wang, HM
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visa fler...
-
Sha, YL
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Xu, GZ
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Styring, Stenbjö ...
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Huang, P
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visa färre...
- Om ämnet
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
- Artiklar i publikationen
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Journal of Coord ...
- Av lärosätet
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Lunds universitet